Investigaciones

Publicaciones de nuestros profesores y asociados

2022

Speciation study and biological activity of copper (II) complexes with picolinic and 6-methylpicolinic acid with different components of blood serum of low molecular mass in KNO3 1.0 mol•L−1 at 25 °C. 

Revista: Polyhedron.

Edgar Del Carpio, María L. Serrano, Lino Hernández, Waleska Madden, Vito Lubes, Vanessa R. Landaeta, Rafael E. Rodríguez-Lugo, Giuseppe Lubes, Anita Stern, Carlos Ciangherotti, Lissette Jiménez

2021

Applying Bayesian forecasting to predictive toxicology: The probability of innate carcinogenicity to humans of colorants synthesized from benzidine. 

Revista: Toxicology Letters.

Suarez-Torres JD, Orozco CA, Ciangherotti Carlos

 

Actividad de las enzimas antioxidantes en la enfermedad periodontal en ratas espontáneamente hipertensas. Efecto del Valsartán

Revista: Revista de la Facultad de Farmacia UCV

María Gabriela Matos, Leticia FiGueira, Marco Álvarez, Lourdes PerdoMo, Anita Israel, María del Rosario Garrido

 

Efecto del extracto acuoso de la raíz de Ruellia tuberosa L. sobre la activación de las ERK 1/2 renal en ratas con diabetes inducida por la estreptozotocina

Revista: Revista de la Facultad de Farmacia UCV

Carlos Ciangherotti, Mariella Pastorello, Giovannina Orsini, Lourdes Perdomo, Marco Álvarez y Anita Israel.

 

The 2-year rodent bioassay in drug and chemical carcinogenicity testing: Performance, utility, and configuration for cancer hazard identification.

Revista: Journal of Pharmacological and Toxicological Methods

Suarez-Torres JD, Orozco CA, Ciangherotti Carlos

 

The numerical probability of carcinogenicity to humans of some pharmaceutical drugs: alkylating agents, topoisomerase inhibitors or poisons, and DNA intercalators

Revista: Fundamental & Clinical Pharmacology 

Suarez-Torres JD, Orozco CA, Ciangherotti Carlos

 

The numerical probability of carcinogenicity to humans of some antimicrobials: Nitro-monoaromatics (including 5-nitroimidazoles), quinoxaline-1,4-dioxides (including carbadox), and chloramphenicol

Revista: Toxicology in vitro 

Suarez-Torres JD, Orozco CA, Ciangherotti Carlos

 

 

2020

Ghrelin and C Peptide as biomarkers for hypercholesterolemia. 

Revista: Gaceta Médica de Caracas   

Figueira L, Mathison Y, Pastorello M,   Matos María Gabriela,  Camacho E, Romero E,  Hernández J,  Garrido MR, Billet E,  López Y, Israel A.

 

The predictivity of the -alert performance- functionality of the OECD QSAR-Toolbox (c/w further issues on the predictivity of nonclinical testing)

Revista: Toxicology in vitro

Suarez-Torres JD, Ciangherotti Carlos, Jimenez-Orozco FA

 

Synthesis of Iron Nanoparticles from aqueous extract of Eucalyptus robusta Sm and evaluation of antioxidant and antimicrobial activity

Revista: Materials Science for Energy Technologies

Yosmery Vitta, Maice Figueroa, María Calderon, Carlos Ciangherotti

 

Insights into toxicology, safety pharmacology, and drug dependence testing: The performance and predictive values of nonclinical tests

Revista: Journal of Pharmacological and Toxicological Methods

Suarez-Torres JD, Ciangherotti Carlos, Jimenez-Orozco FA 

 

The 2-year rodent bioassay in drug and chemical carcinogenesis testing: Sensitivity, according to the framework of carcinogenic action

Revista: Toxicology Mechanisms and Methods

Suarez-Torres JD, Jimenez-Orozco FA, Ciangherotti Carlos

 

C-peptide as a biomarker in preeclampsia.

Revista:  Gaceta Médica de Caracas 

Camacho E, Matos María Gabriela, Cortez R, Israel A.

 

Efecto del valsartan sobre las vías señalización del receptor TRL4 en la enfermedad periodontal experimental. 

Revista: Revista de la Facultad de Farmacia  UCV   

Matos María Gabriela,  Álvarez M,  Perdomo L, Garrido MR, Israel A.

 

Drug excipients, food additives, and cosmetic ingredients probably not carcinogenic to humans reveal a functional specificity for the 2-year rodent bioassay

Revista: Journal of Applied Toxicology

Suarez-Torres JD, Jimenez-Orozco FA, Ciangherotti Carlos